BRFK 140

Lda 140

Dmd048736 132..140

Knockout mouse models targeting various cytochrome P450 (P450 or CYP) genes are valuable for determining P450’s biologic functions, including roles in drug metabolism and chemical toxicity. In this study, a novel Cyp2a(4/5)bgs-null mouse model was generated, in which a 1.2-megabase pair genomic fragment containing nine Cyp genes in mouse chromosome 7 (including, sequentially, Cyp2a5, 2g1, 2b19,...

Pns1200295 140..152

The purpose of this review was to update available knowledge on the relationship between adherence to the Mediterranean diet (MeDi) and cognitive decline, risk of dementia or Alzheimer’s Disease (AD), and to analyse the reasons for some inconsistent results across studies. The traditional MeDi has been recognised by the United Nations Educational Scientific and Cultural Organisation as an Intan...

Dmd054957 134..140

Inflammation and infection downregulate the activity and expression of cytochrome P450s (P450s) and other drug metabolizing enzymes (DMEs) involved in hepatic drug clearance. Schistosoma mansoni infection was reported to cause a downregulation of hepatic P450-dependent activities in mouse liver, but little is known about the specific enzymes affected or whether phase II DMEs are also affected. ...

140-148 Sultana

Over the past decade, interest in evaluating oriental medicinal herbs and edible phytoproducts for use in cancer preventive strategies is encouraging and emerging as an acceptable approach for controlling the cancer incidence in many developing as well as developed countries (Kellof, 2000). Several experimental evidence for all common cancer sites have indicated that intake of fruits and vegeta...